Once running Magento 2 CLI Command
php bin/magento setup:upgrade or any other CLI Command
& getting error as
Can't run this operation: deployment configuration is absent. Run 'magento setup:config:set --help' for options.

Solution : This error getting, while Magento 2 Database Configuration file env.php [app/etc/env.php], not available
Once Database Configuration file env.php [app/etc/env.php] available , issue will be resolved.